
The team of researchers from the Gladstone Institute suggests that a diet that emphasizes low-calorie diet and carbohydrates that can trigger the production of a compound that plays an important role in delaying the aging process.
If the concentration is low, a compound called beta-hydroxybutyrate (beta-OHB) or 'ketone body' can help protect body cells from oxidative stress that contributes to the aging process.
Oxidative stress occurs when the body's cells use oxygen to produce energy but besides that this activity also resulted in the release of other toxic molecules known as free radicals.
The problem is when the age, the body's cells are no longer effective in clearing these molecules free radicals causing cell damage, oxidative stress and the effects of aging. But the researchers found that beta-OHB was really able to help delay the process.
It was found that beta-OHB, one of the body's main source of energy during exercise or fasting, can inhibit the formation of an enzyme that promotes the emergence of 'oxidative stress' and protects cells from aging.
These findings obtained by the research team after passing a series of experiments involving a number of participants were asked to chronic calorie restriction diet. From there it was seen that calorie restriction triggers the production of beta-OHB that can inhibit the activity of a group of enzymes called histone deacetylase, or HDAC.
Investigate a calibaration, apparently normal existence HDAC this 'work' deadly pair of genes called Foxo3a and MT2. But with increased levels of beta-OHB, these compounds can inhibit HDAC doing it or in other words a pair of genes had finally become active. Whereas once activated, they can start an activity to help the body's cells against oxidative stress siege.
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